人 GDNF ELISA 试剂盒

Name: 人 GDNF ELISA 试剂盒
Brand: SIGMA

for serum, plasma, cell culture supernatant and urine

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所有图片(2)

About This Item

UNSPSC代码:

41116158

NACRES:

NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type serum
sample type urine
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... GDNF(2668)

一般描述

Glial cell derived neurotrophic factor (GDNF) is encoded by the gene mapped to human chromosome 5p14.1−q13.3. It belongs to the transforming growth factor β (TGF-β) superfamily. GDNF is abundantly found in gliomas.

免疫原

Recombinant Human GDNF

应用

请参考Protocol了解详情。

生化/生理作用

Glial cell derived neurotrophic factor (GDNF) is a neurotrophic factor involved in dopaminergic and neurodevelopment. It plays a vital role in self-renewal of stem cells. In addition, GDNF also facilitates differentiation of chained undifferentiated spermatogonia. GDNF with its receptors, activates various signaling pathways essential for maintaining cellular homeostasis. Mutated gene is associated with the development of schizophrenia. GDNF is a potential target for treating Parkinson′s disease.