人类 ShhN ELISA 试剂盒

Name: 人类 ShhN ELISA 试剂盒
Brand: SIGMA

for serum, plasma, cell culture supernatants and urine

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About This Item

UNSPSC代码:

41116158

NACRES:

NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 42 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent C)
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent B)

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... SHH(6469)

一般描述

The Human Shh-N (Sonic Hedgehog N Terminus) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human Shh-N in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human ShhN

应用

请参考Protocol了解详情。

生化/生理作用

Sonic hedgehog (Shh) is a secreted glycoprotein involved in embryonic morphogenic development of several tissues. It has a role in fracture healing and regeneration. In the canonical pathway, the protein associates with its receptor patched (Ptc-1), de-represses smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. Shh plays a vital role in axon growth and guidance throughout the brain development. Shh stimulates neurite outgrowth by overcoming neurite growth inhibitory environment associated with glial scar.