S0266
精脒
BioReagent, Molecular Biology, suitable for cell culture, ≥98%
别名:
1,8-二氨基-4-氮杂辛烷, N-(3-氨基丙基)-1,4-丁烷
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关于此项目
线性分子式:
NH2(CH2)3NH(CH2)4NH2
化学文摘社编号:
分子量:
145.25
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
204-689-0
Beilstein/REAXYS Number:
1698591
MDL number:
grade
Molecular Biology
Quality Level
product line
BioReagent
assay
≥98%
form
solid or liquid
mol wt
145.25 (AMU)
technique(s)
cell culture | mammalian: suitable
refractive index
n20/D 1.479 (lit.)
density
0.925 g/mL at 25 °C (lit.)
foreign activity
DNase, RNase, and protease, none detected
storage temp.
room temp
SMILES string
NCCCCNCCCN
InChI
1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
InChI key
ATHGHQPFGPMSJY-UHFFFAOYSA-N
Gene Information
rat ... Ppm1a(24666)
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General description
亚精胺属于天然多胺，存在于叶绿体、细菌或真核细胞中。
Application
亚精胺可用于制备金珠并用作核分离缓冲液（NIB）成分。
精胺适合用于分子生物缓冲液和> 100 bp DNA沉淀。它被用来在植物和哺乳动物细胞中，通过粒子轰击技术，传递DNA。
Biochem/physiol Actions
亚精胺有助于维持基因表达的正常活性。此多胺在中间代谢中起关键作用。也可用作E1A相关蛋白p300（EP300）乙酰转移酶活性的抑制剂。亚精胺参与细胞生长。
抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA，可用于DNA结合蛋白纯化。激活T4聚核苷酸激酶活性。
抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA；激活T4聚核苷酸激酶活性。
Disclaimer
如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
233.6 °F - closed cup
flash_point_c
112 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Elumalai Sivamani et al.
Plant cell reports, 28(2), 213-221 (2008-11-19)
We have developed a method by which remarkably higher efficiencies of transient and stable transformation were achieved in bombardment transformation of plants. Over fivefold increase in transient gus gene expression was achieved when rice or maize suspension cells were bombarded
Spermidine delays aging in humans
Madeo F, et al.
Aging (Albany. NY.), 10(8), 2209-2209 (2018)
Delivery of DNA to skin by particle bombardment.
Shixia Wang et al.
Methods in molecular biology (Clifton, N.J.), 245, 185-196 (2004-01-07)
Molecular Determinants of Metaplastic and Neoplastic Transformation in the Esophageal Epithelium
Progress in Molecular Biology and Translational Science, 96, 63-92 (2010)
Organization, developmental dynamics, and evolution of plastid nucleoids
Sato N, et al.
International Review of Cytology, 232, 217-262 (2003)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S0266-25G | 04061836830175 |
| S0266-5G | 04061837898983 |
| S0266-1G | 04061836830168 |
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