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Merck
CN

S6764

[pGlu6, Pro9]-Substance P fragment 6-11

≥95% (HPLC)

别名:

Septide, pGlu-Phe-Phe-Pro-Leu-Met-NH2

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关于此项目

经验公式(希尔记法):
C39H53N7O7S
化学文摘社编号:
分子量:
763.95
UNSPSC Code:
12352200
MDL number:
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assay

≥95% (HPLC)

storage temp.

−20°C

Biochem/physiol Actions

A potent and selective NK-1 tachykinin receptor agonist.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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John M T Chu et al.
Neuropharmacology, 61(8), 1389-1398 (2011-09-13)
Neurokinin one (NK1) receptor is Substance P (SP) receptor and it is abundantly distributed in the basal ganglia. Growing evidences were shown on their possible roles in the pathogenesis and treatment of Parkinson's disease (PD). NK1 receptor is a kind
F Y Chang et al.
Journal of gastroenterology and hepatology, 14(1), 39-45 (1999-02-24)
Natural neurokinins (NK) and their specific receptor agonists, including substance P (SP), neurokinin A (NKA), neurokinin B (NKB), septide, [NIe10]-NKA4-10 and senktide, were used to assess whether they could activate established NK receptors in rat gastrointestinal tract and central nervous
Heiko U De Schepper et al.
Regulatory peptides, 130(3), 105-115 (2005-06-07)
Tachykinins are important mediators in neuromuscular signalling but have not been thoroughly characterised in the mouse gut. We investigated the participation of tachykinin receptors in contractility of circular muscle strips of the mouse ileum. Electrical field stimulation (EFS) of excitatory