方案
≥98%
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
C[C@H]1CC[C@@]2(OC1)O[C@H]3C[C@H]4[C@@H]5CC[C@@H]6C[C@@H](O)CC[C@]6(C)[C@H]5CC[C@]4(C)[C@H]3[C@@H]2C
InChI
1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21-,22-,23-,24-,25-,26-,27+/m0/s1
InChI key
GMBQZIIUCVWOCD-WWASVFFGSA-N
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一般描述
Sarsasapogenin also known as Sarsagenin or Parigenin, is a steroidal saponin and is the main constituent of Anemarrhena asphodeloides Bunge.
应用
Sarsasapogenin has been used as a synthetic saponin treatment to U-2 OS cells to test its effects in reducing osteosarcoma cell viability and down-regulating YAP and TAZ proteins.
生化/生理作用
Sarsasapogenin is a well-known multi-target directed ligand (MTDL) for Alzheimer′s disease. It elicits anti-inflammatory, antioxidant, anti-arthritis, anti-asthma, anti-amyloidogenic, neuroprotective, anti-depressant, and anti-cancer properties. SAR also improves learning and memory ability, loss of neurons in type-1 diabetic rats and protects against diabetic encephalopathy. It is also a therapeutic target for treating ulcerative colitis (UC). SAR as an anti-inflammatory agent improves insulin resistance and adipose tissue inflammation in high-fat diet (HFD)-fed mice.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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