SAB1300134
Monoclonal Anti-SET07 antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
别名:
Anti-H4-K20-HMTase, Anti-Histone H4-K20 methyltransferase, Anti-PR/SET07, PR/SET domain-containing protein 07, SET domain-containing protein 8
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
43AT890, monoclonal
Application:
ELISA (i), WB
Citations:
-
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
43AT890, monoclonal
form
buffered aqueous solution
species reactivity
human, mouse
technique(s)
indirect ELISA: 1:1000, western blot: 1:100-1:500
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SET07(387893)
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General description
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
Immunogen
SET07 (AAF97812, N Terminal)
This antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SET07.
This antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SET07.
Physical form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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