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Merck
CN
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主要文件

SAB1300159

Sigma-Aldrich

Anti-SET07 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-H4 lysine-20 specific, Anti-H4-K20-HMTase, Anti-Histone H4-K20 methyltransferase, Anti-Histone-lysine N-methyltransferase, SET domain-containing protein 8

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

技术

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... SET07(387893)

一般描述

SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.

免疫原

SET07 (AAF97812, Full length)
This antibody is generated from rabbits immunized with a recombinant protein encoding full length human SET07.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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