SAB1300159
Anti-SET07 antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
别名:
Anti-H4 lysine-20 specific, Anti-H4-K20-HMTase, Anti-Histone H4-K20 methyltransferase, Anti-Histone-lysine N-methyltransferase, SET domain-containing protein 8
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC
Citations:
-
antibody product type
primary antibodies
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SET07(387893)
General description
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
Immunogen
SET07 (AAF97812, Full length)
This antibody is generated from rabbits immunized with a recombinant protein encoding full length human SET07.
This antibody is generated from rabbits immunized with a recombinant protein encoding full length human SET07.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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