SAB1408844
Anti-PCMTD1 antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
别名:
FLJ10883
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 40.7 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PCMTD1(115294)
General description
The gene PCMTD1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) is mapped to human chromosome 8q. Single nucleotide polymorphism at rs1015213, which is present in the intergenic region between PCMTD1 and ST18 (suppression of tumorigenicity 18), is associated with primary angle closure glaucoma. However, it is not responsible for any phenotypic diversity in the disease severity or progression.
Immunogen
PCMTD1 (NP_443169.1, 1 a.a. ~ 357 a.a) full-length human protein.
Sequence
MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDIKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK
Sequence
MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDIKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK
Physical form
Solution in phosphate buffered saline, pH 7.4
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Association of PLEKHA7, COL11A1 and PCMTD1-ST18 gene polymorphisms with primary angle closure glaucoma in ethnic Han Chinese from Sichuan.
Tan C
Zhonghua yi xue yi chuan xue za zhi (Chinese Journal of Medical Genetics), 33, 545-549 (2016)
Genotype-phenotype correlation analysis for three primary angle closure glaucoma-associated genetic polymorphisms.
Wei X
Investigative Ophthalmology & Visual Science, 55, 1143-1148 (2014)
Association study in a South Indian population supports rs1015213 as a risk factor for primary angle closure.
Duvesh R
Investigative Ophthalmology & Visual Science, 54, 5624-5628 (2013)
Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.
Day AC
The British Journal of Ophthalmology, 97, 704-707 (2013)
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