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主要文件

SAB2109182

Sigma-Aldrich

Anti-TCIM (N-terminal) antibody produced in rabbit

affinity isolated antibody

别名:

C8orf4, TC-1, TC1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

12 kDa

种属反应性(根据同源性预测)

horse, rabbit, guinea pig, canine, rat, bovine, human, mouse

浓度

0.5 mg/mL

技术

western blot: 1 μg/mL

NCBI登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... TCIM(57396)

一般描述

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

免疫原

Synthetic peptide directed towards the N-terminal region of Human C8orf4

序列

Synthetic peptide located within the following region: TASRKKAVGNIFENTDQESLERLFRNSGDKKAEERAKIIFAIDQDVEEKT

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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