SAB2501651
Anti-CREB3L1 (C-terminal) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
BBF-2 (Drosophila) homolog, CAMP responsive element binding protein 3-like 1, Old astrocyte specifically induced substance
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
2
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CREB3L1(90993)
General description
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) belongs to the CREB family of transcription factors. It has a bZIP (basic-leucine zipper) domain and a DNA binding domain. The gene encoding this protein is mapped to human chromosome 11 and is expressed in many tissues.
Immunogen
Peptide with sequence DFSHSKEWFHDRD, from the C-terminal region of the protein sequence according to NP_443086.1
Biochem/physiol Actions
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) is an unfolded protein response (UPR) transducer. It localizes in the endoplasmic reticulum. In the presence of UPR signaling, CREB3L1 is cleaved and the amino terminal part is translocated to the nucleus. The nuclear part regulates target gene expression. CREB3L1 is involved in the differentiation and development of astrocytes, osteoblasts, odontoblasts, pancreatic beta-cells and large intestine goblet cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis.
Ahn JI
Current Molecular Medicine (2016)
Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers.
Ward AK
Breast Cancer Research (2016)
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