SAB2702380
Monoclonal Anti-HEC1 antibody produced in mouse
clone 9G3.23, affinity isolated antibody
别名:
HEC, HEC1, HsHec1, KNTC2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
9G3.23, monoclonal
Application:
FACS, ICC, IF, IHC, IP, PLA, WB
Citations:
1
biological source
mouse
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
9G3.23, monoclonal
form
buffered aqueous solution
mol wt
80kDa
species reactivity
hamster, kangaroo rat, human
concentration
1mg/mL
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, proximity ligation assay: suitable, western blot: suitable
isotype
IgG2a
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NDC80(10403)
Immunogen
Human HEC1 protein consisting of amino acids 56-642.
Application
Suggested starting dilutions are as follows: FACS: Assay-dependent dilution, ICC/IF: 1:100-1:1000, IHC: Assay-dependent dilution, IP: Assay-dependent dilution, WB: 1:500-1:3000, PLA: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Biochem/physiol Actions
Human HEC 1 is a coiled-coil protein that has been demonstrated to have a role in M-phase progression. It is essential for proper chromosome segregation. Its depletion results inthe impairment of chromosome congression and results in spindle checkpoint activation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Phosphate-buffered saline, no preservative added.
Other Notes
Purification: Protein G Affinity Purified
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Geethu E Thomas et al.
Nature communications, 7, 11665-11665 (2016-05-27)
Kinetochore couples chromosome movement to dynamic microtubules, a process that is fundamental to mitosis in all eukaryotes but poorly understood. In vertebrates, spindle-kinetochore-associated (Ska1-3) protein complex plays an important role in this process. However, the proteins that stabilize Ska-mediated kinetochore-microtubule
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