biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
15S2G6, monoclonal
form
buffered aqueous solution
mol wt
antigen ~90 kDa
species reactivity
canine, rat, monkey, bovine, human
concentration
~1.0 mg/mL
technique(s)
flow cytometry: 20 μg/test using A549 cells, immunoblotting: 0.5-1.0 μg/mL using NT2/D1 total cell extracts, immunofluorescence: 20 μg/mL using PC12 or A549 cells
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... EXOC6(50556)
General description
Monoclonal Anti-EXOC6 (mouse IgG1 isotype) is derived from the hybridoma 15S2G6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant protein corresponding to full-length rat brain EXOC6 subunit. Exocyst complex component 6 (EXOC6) is located on the human chromosome at 10q23.33.
Immunogen
a recombinant protein corresponding to full-length rat brain EXOC6 subunit.
Application
Monoclonal Anti-EXOC6 antibody has been used in
- immunoblotting
- immunofluorescence
- flow Cytometry
- immunocytochemistry
Biochem/physiol Actions
Exocyst complex component 6 (EXOC6) has been shown to interact with the Rab11 (Ras-related protein), a GTPase that regulates both biosynthetic and endocytic traffic. This interaction results in endocytic trafficking directed toward the apical and basolateral poles of polarized cells.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility
Wei S, et al.
Carcinogenesis, 33(8), 1531-1537 (2012)
Rab proteins and the compartmentalization of the endosomal system
Wandinger-Ness A and Zerial M
Cold Spring Harbor Perspectives in Biology, 6(11), a022616-a022616 (2014)
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