SAB4300160
Anti-phospho-BCR (pTyr177) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-ALL antibody produced in rabbit, Anti-BCR-ABL1 antibody produced in rabbit, Anti-BCR1 antibody produced in rabbit, Anti-CML antibody produced in rabbit, Anti-breakpoint cluster region antibody produced in rabbit
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), WB
Citations:
1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~210 kDa
species reactivity
mouse, human
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(P-F-YP-V-N)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr177)
Gene Information
human ... BCR(613)
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General description
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Immunogen
Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N), according to the protein BCR.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yuki Tanaka et al.
Journal of immunology (Baltimore, Md. : 1950), 201(8), 2256-2263 (2018-09-12)
We recently reported that NF-κB-mediated inflammation caused by breakpoint cluster region (BCR) is dependent on the α subunit of casein kinase II (CK2α) complex. In the current study, we demonstrate that presenilin 1 (Psen1), which is a catalytic component of
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