SAB4300492
Anti-CDC2 (Ab-15) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-CDC28A antibody produced in rabbit, Anti-CDK1 antibody produced in rabbit, Anti-DKFZp686L20222 antibody produced in rabbit, Anti-MGC111195 antibody produced in rabbit, Anti-cell division cycle 2, G1 to S and G2 to M antibody produced in rabbit
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~34 kDa
species reactivity
human, rat, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(G-T-Y-G-V)
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CDC2(983)
General description
CDC2/CDK1 (cyclin-dependent kinase 1) belongs to the Ser/Thr protein kinase family. It is located on human chromosome 10q21.
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Immunogen
Peptide sequence around aa. 13-17 (G-T-Y-G-V), according to the protein CDC2.
Biochem/physiol Actions
CDC2/CDK1 (cyclin-dependent kinase 1) controls various mitotic processes like reorganization of the cytoskeleton, segregation of chromosome, formation and separation of daughter cells. It is essential for the multiplication of mammalian cell. It participates in tumorigenesis.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
Bieche I, et al.
Molecular Cancer, 10:23 (2011)
Recurrent CDK1 overexpression in laryngeal squamous cell carcinoma
Bednarek K, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(8), 11115-11126 (2016)
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics
Petrone A, et al.
Molecular and Cellular Proteomics, 15(7), 2448-2461 (2016)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持