SAB4500626
Anti-DCT antibody produced in rabbit
affinity isolated antibody
别名:
DCT, DT, L-dopachrome δ-isomerase, L-dopachrome tautomerase, Tyrosinase-related protein 2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 59 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TYRP2(1638)
General description
Anti-DCT Antibody detects endogenous levels of total DCT protein.
Dopachrome tautomerase (DCT) is also termed as tyrosinase-related protein 2 (TYRP2). It is present in melanocytes, RPE (retinal pigment epithelium) cells and HaCaTs (basal keratinocytes). It is located on human chromosome 13q32.
Immunogen
The antiserum was produced against synthesized peptide derived from human DCT.
Immunogen Range: 51-100
Immunogen Range: 51-100
Biochem/physiol Actions
Dopachrome tautomerase (DCT) participates in the production of melanin in melanosomes and also in the detoxification of the melanin precursors. It restricts the destructions induced by chemotherapeutic agents like X-ray or UVB (ultraviolet B) and gamma irradiation in melanoma cells and reduces the susceptibility of cell to oxidative stress.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
The Role of DCT in HPV16 Infection of HaCaTs
Aksoy P and Meneses PI
PLoS ONE (2017)
Finding genes that underlie physical traits of forensic interest using genetic tools
Pulker H, et al.
Forensic Science International. Genetics, 1(2), 100-104 (2007)
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