biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 25 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TK1(7083)
General description
Anti-KITH Antibody detects endogenous levels of total KITH protein.
The Thymidine kinase 1 (TK1) gene is mapped to human chromosome 17q25.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human KITH.
Immunogen Range: 161-210
Immunogen Range: 161-210
Biochem/physiol Actions
Thymidine kinase 1 (TK1) takes part in the process of DNA synthesis. It catalyzes the formation of pyrimidine deoxynucleotides through salvage pathway. The enzyme is an ATP dependent kinase. TK1 serves as a biomarker, indicating the recurrence of tumor and metastasis of cancer including gastrointestinal cancer, leukemia and lymphoma.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Expression and Clinical Significance of Cytokeratin-19 and Thymidine Kinase-1 in Advanced Gastrointestinal Cancer.
Du YY
Chinese Medical Journal (English Edition), 129(18), 2168-2172 (2016)
Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas.
Heimann P
Cancer Research, 61(10), 4130-4135 (2001)
Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.
D'Costa Z
Cancer Research, 77(21), 5952-5962 (2017)
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