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Merck
CN

SAB5701873

Anti-Phospho-ATF2-T71 antibody produced in rabbit

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
monoclonal
Species reactivity:
mouse, human, rat
Application:
IHC, WB
Citations:
-
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biological source

rabbit

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

mouse, human, rat

concentration

0.52 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr71)

Quality Level

Gene Information

human ... ATF2(1386)

General description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]

Immunogen

A phospho specific peptide corresponding to residues surrounding T71 of human ATF2

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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