Anti-Phospho-BRD4-S1070 antibody produced in rabbit

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

A phospho synthetic peptide corresponding to residues surrounding S1070 of Human Phospho-BRD4-S1070.

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.