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Merck
CN

SMB01048

Uzarin

≥90% (LC/MS-ELSD)

别名:

(3beta,5alpha)-3-((6-O-beta-D -glucopyranosyl-beta-D -glucopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, Uzarigenin 3-β-sophoroside

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关于此项目

经验公式(希尔记法):
C35H54O14
化学文摘社编号:
分子量:
698.79
UNSPSC Code:
12352205
NACRES:
NA.25
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SMILES string

O1CC(=CC1=O)[C@@H]2[C@@]3([C@@]([C@H]4[C@@H]([C@@]5([C@H](C[C@H](CC5)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)O)O)CO)CC4)C)CC3)(CC2)O)C

InChI

1S/C35H54O14/c1-33-8-5-18(46-32-30(28(42)26(40)23(14-37)48-32)49-31-29(43)27(41)25(39)22(13-36)47-31)12-17(33)3-4-21-20(33)6-9-34(2)19(7-10-35(21,34)44)16-11-24(38)45-15-16/h11,17-23,25-32,36-37,39-44H,3-10,12-15H2,1-2H3/t17-,18-,19+,20-,21+,22+,23+,25+,26+,27-,28-,29+,30+,31-,32+,33-,34+,35-/m0/s1

InChI key

RIPMDUQTRRLJTE-QHYHXNCWSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

698.79

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Uzarin, also known as Uzarigenin, is a cardenolide glycoside commonly found in plants such as Xysmalobium undulatum, Nerium oleander, Asclepias fruticosa, and Calotropis procera. Existing research suggests that this plant-derived metabolite exerts multiple biological properties, including antidiarrheal, antiviral and anticancer.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

According to the existing research, Uzarin plays potential role as an inhibitor of the SARS-CoV-2 receptor binding domain and SARS-CoV-2 RNA-dependent polymerase, as indicated by molecular docking and dynamics studies.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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