T1016
Trichlormethiazide
≥98%
别名:
6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
(+/-)-, NSC 61560
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关于此项目
经验公式（希尔记法）:
C8H8Cl3N3O4S2
化学文摘社编号:
分子量:
380.66
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-118-8
MDL number:
Quality Level
assay
≥98%
SMILES string
NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl
InChI
1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
InChI key
LMJSLTNSBFUCMU-UHFFFAOYSA-N
Gene Information
human ... SLC12A3(6559)
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signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Susumu Ogawa et al.
Hypertension (Dallas, Tex. : 1979), 47(4), 699-705 (2006-03-01)
We tested the hypothesis that blockade of angiotensin II type 1 receptors reduces oxidative stress markers in parallel with urinary albumin and type IV collagen excretions. Sixty-six diabetic patients with nephropathy were randomly assigned to either the angiotensin II receptor
I Kuwajima et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 24(5), 475-480 (2001-10-26)
A randomized prospective controlled study, the National Interventional Cooperative Study in Elderly Hypertensives (NICS-EH), previously demonstrated that the preventive effect of the long-acting calcium channel blocker nicardipine on the cardiovascular endpoint was similar to that of the diuretic, trichlormethiazide. The
Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker.
Kenichiro Miura et al.
Pediatric nephrology (Berlin, Germany), 24(6), 1235-1238 (2009-01-21)
The administration of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs) to pregnant women has been reported to cause ACEI/ARB fetopathy, including oligohydramios, pulmonary hypoplasia, renal insufficiency, limb contracture, and fetal hypotension in the child. Most of
Yasuo Takahashi et al.
Cardiovascular diabetology, 10, 45-45 (2011-05-25)
Trichlormethiazide, a thiazide diuretic, was introduced in 1960 and remains one of the most frequently used diuretics for treating hypertension in Japan. While numerous clinical trials have indicated important side effects of thiazides, e.g., adverse effects on electrolytes and uric
Takeshi Takami
Hypertension research : official journal of the Japanese Society of Hypertension, 32(12), 1086-1090 (2009-09-26)
Morning hypertension has been reported to be an important risk factor for cardiovascular events, and arterial stiffness bears a relationship with cardiovascular risk. The aim of this study was to evaluate whether high-dose angiotensin II receptor blocker (ARB) treatment has
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T1016-5G | 04061837336379 |
| T1016-1G | 04061837336331 |
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