WH0005495M1
Monoclonal Anti-PPM1B antibody produced in mouse
clone 1A3-2A4, purified immunoglobulin, buffered aqueous solution
别名:
Anti-MGC21657, Anti-PP2CB, Anti-PP2CBETA, Anti-PP2CbetaX, Anti-PPC2BETAX, Anti-protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Technique(s):
immunoprecipitation (IP): suitable, immunofluorescence: suitable, indirect ELISA: suitable, proximity ligation assay: suitable, western blot: 1-5 μg/mL
Conjugate:
unconjugated
Application:
ELISA (i), IF, IP, PLA, WB
Citations:
-
technique(s)
immunoprecipitation (IP): suitable, immunofluorescence: suitable, indirect ELISA: suitable, proximity ligation assay: suitable, western blot: 1-5 μg/mL
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1A3-2A4, monoclonal
form
buffered aqueous solution
species reactivity
human
isotype
IgG1κ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PPM1B(5495)
General description
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. (provided by RefSeq)
Immunogen
PPM1B (AAH12002, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
Sequence
MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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