A1474
Monoclonal Anti-β-Amyloid (1-17) antibody produced in mouse
~1 mg/mL, clone 6E10, purified immunoglobulin, buffered aqueous solution
antibody form
purified immunoglobulin
clone
6E10, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
~1 mg/mL
technique(s)
immunohistochemistry: 1:100-1:1000, immunoprecipitation (IP): 1:10-1:100, indirect ELISA: 1:103-1:105, western blot: 1:100-1:1000
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... APP(351)
Immunogen
synthetic peptide corresponding to amino acids 1-17 of the human β amyloid peptide with Glu substituted at position 11, conjugated to KLH.
Physical form
Solution in phosphate buffered saline with 0.03 % thimerosal.
法规信息
新产品
此项目有
David A Bateman et al.
BMC neuroscience, 8, 29-29 (2007-05-04)
Aggregation of the amyloid peptides, Abeta40 and Abeta42, is known to be involved in the pathology of Alzheimer's disease (AD). Here we investigate the relationship between peptide aggregation and cell surface binding of three forms of Abeta (Abeta40, Abeta42, and
A Law et al.
Brain research. Brain research reviews, 35(1), 73-96 (2001-03-14)
Alzheimer's disease (AD) is the most common form of dementia, with progressive cognitive deficits being the primary symptom. AD is neuropathologically characterized by amyloid and neurofibrillary tangle depositions, basal forebrain cholinergic deficit, and extensive neuronal loss and synaptic changes in
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