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Merck
CN

A1474

Sigma-Aldrich

Monoclonal Anti-β-Amyloid (1-17) antibody produced in mouse

~1 mg/mL, clone 6E10, purified immunoglobulin, buffered aqueous solution

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MDL编号:
UNSPSC代码:
12352203
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抗体形式

purified immunoglobulin

克隆

6E10, monoclonal

表单

buffered aqueous solution

种属反应性

human

浓度

~1 mg/mL

技术

immunohistochemistry: 1:100-1:1000
immunoprecipitation (IP): 1:10-1:100
indirect ELISA: 1:103-1:105
western blot: 1:100-1:1000

运输

dry ice

储存温度

−20°C

基因信息

human ... APP(351)

免疫原

synthetic peptide corresponding to amino acids 1-17 of the human β amyloid peptide with Glu substituted at position 11, conjugated to KLH.

外形

Solution in phosphate buffered saline with 0.03 % thimerosal.

法规信息

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David A Bateman et al.
BMC neuroscience, 8, 29-29 (2007-05-04)
Aggregation of the amyloid peptides, Abeta40 and Abeta42, is known to be involved in the pathology of Alzheimer's disease (AD). Here we investigate the relationship between peptide aggregation and cell surface binding of three forms of Abeta (Abeta40, Abeta42, and
A Law et al.
Brain research. Brain research reviews, 35(1), 73-96 (2001-03-14)
Alzheimer's disease (AD) is the most common form of dementia, with progressive cognitive deficits being the primary symptom. AD is neuropathologically characterized by amyloid and neurofibrillary tangle depositions, basal forebrain cholinergic deficit, and extensive neuronal loss and synaptic changes in

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