Monoclonal Anti-Na⁺/K⁺ ATPase (β1 Subunit) antibody produced in mouse

Epitope mapping studies indicate that this clone recognizes the epitope between amino acids 195 and 199 of the sheep β1 subunit of Na⁺/K⁺ ATPase. Staining is consistent with the plasma membrane localization of Na⁺/K⁺ ATPase.

Mouse monoclonal anti-Na⁺/K⁺ ATPase (β1 subunit) reacts with the β1 subunit of Na⁺/K⁺ ATPase in humans, sheep, canines and pigs, but not in rats. The product shows no reactivity with rat β2 subunit. In immunoblotting, the antibody detects the β1 subunit of Na⁺/K⁺ ATPase as a 42kDa band in liver samples, and as a 52kDa band in kidney samples.

Na⁺/K⁺ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.

lamb kidney β subunit of Na⁺/K⁺ ATPase.

Mouse Monoclonal Anti-Na⁺/K⁺ ATPase (β1 subunit) can be used in immunohistochemical (1:100) and western blot (1:1,000 - 1:10,000) applications

Solution in phosphate buffered saline with 1mg/ml BSA and 0.05% sodium azide

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