方案
≥95% (HPLC)
储存温度
−20°C
SMILES字符串
CC(C)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)CCC[C@H](N)C(O)=O)C(=O)N[C@H](C(C)C)C(O)=O)NC(=O)CCC[C@H](N)C(O)=O)C(O)=O
其他说明
ACV is the key intermediate in the biosynthesis of all penicillins and cephalosporins by eukaryotic and prokaryotic microorganisms.
法规信息
新产品
此项目有
W Kallow et al.
FEBS letters, 414(1), 74-78 (1997-09-26)
The tripeptide delta-L-alpha-aminoadipyl-L-cysteinyl-D-valine (LLD-ACV) is synthesised by the multifunctional enzyme ACV synthetase integrating four steps of the penicillin and cephalosporin biosynthetic pathway. Peptide synthesis follows the thiotemplate mechanism from intermediates bound as thioesters to the enzyme. The formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-thioester
P Adriaens et al.
Antimicrobial agents and chemotherapy, 8(6), 638-642 (1975-12-01)
Cultures of Penicillium chrysogenum, growth with [(35)S]sulfate or labeled amino acids, were examined by ion-exchange chromatography for possible peptidic precursors of penicillin. A sulfur-containing compound, present in both the mycelial extracts and the culture filtrates, was eluted at the location
P L Roach et al.
Nature, 387(6635), 827-830 (1997-06-19)
The biosynthesis of penicillin and cephalosporin antibiotics in microorganisms requires the formation of the bicyclic nucleus of penicillin. Isopenicillin N synthase (IPNS), a non-haem iron-dependent oxidase, catalyses the reaction of a tripeptide, delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine (ACV), and dioxygen to form isopenicillin N
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持