A3105
2-Amino-N-quinolin-8-yl-benzenesulfonamide
≥98% (HPLC), solid
别名:
QBS
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关于此项目
经验公式（希尔记法）:
C15H13N3O2S
化学文摘社编号:
分子量:
299.35
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C15H13N3O2S/c16-12-7-1-2-9-14(12)21(19,20)18-13-8-3-5-11-6-4-10-17-15(11)13/h1-10,18H,16H2
SMILES string
Nc1ccccc1S(=O)(=O)Nc2cccc3cccnc23
InChI key
NIOOKXAMJQVDGB-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
solubility
DMSO: soluble 22 mg/mL, H2O: insoluble
Biochem/physiol Actions
Inhibitor of cell cycle at G2 phase; apoptosis inducer.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Cíntia Tiemi Misugi Kayukawa et al.
Food chemistry, 303, 125388-125388 (2019-08-28)
Saponins are known for their bioactive and surfactant properties, showing applicability to the food, cosmetic and pharmaceutical industries. This work evaluated the saponins effects on Kluyveromyces lactis β-galactosidase activity and correlated these changes to the protein structure. Enzyme kinetic was
Yun-Hee Kim et al.
Biochemical pharmacology, 69(9), 1333-1341 (2005-04-14)
We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cytotoxic compound that induces cell cycle arrest and apoptosis. Treatment of Jurkat T cells with
Minji Kang et al.
ACS applied materials & interfaces, 9(3), 2686-2692 (2016-12-30)
We report on the fabrication of an organic thin-film semiconductor formed using a blend solution of soluble ambipolar small molecules and an insulating polymer binder that exhibits vertical phase separation and uniform film formation. The semiconductor thin films are produced
Mónica Y Herrera-Sotero et al.
Nutrition and cancer, 72(5), 768-777 (2019-08-27)
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