A3105
2-Amino-N-quinolin-8-yl-benzenesulfonamide
≥98% (HPLC), solid
别名:
QBS
方案
≥98% (HPLC)
表单
solid
溶解性
DMSO: soluble 22 mg/mL
H2O: insoluble
SMILES字符串
Nc1ccccc1S(=O)(=O)Nc2cccc3cccnc23
InChI
1S/C15H13N3O2S/c16-12-7-1-2-9-14(12)21(19,20)18-13-8-3-5-11-6-4-10-17-15(11)13/h1-10,18H,16H2
InChI key
NIOOKXAMJQVDGB-UHFFFAOYSA-N
生化/生理作用
Inhibitor of cell cycle at G2 phase; apoptosis inducer.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Yun-Hee Kim et al.
Biochemical pharmacology, 69(9), 1333-1341 (2005-04-14)
We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cytotoxic compound that induces cell cycle arrest and apoptosis. Treatment of Jurkat T cells with
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