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Merck
CN

A3509

Sigma-Aldrich

2-氨基嘌呤

≥99%, synthetic, powder

别名:

2-AP

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关于此项目

经验公式(希尔记法):
C5H5N5
化学文摘社编号:
分子量:
135.13
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
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产品名称

2-氨基嘌呤, ≥99%

生物来源

synthetic

质量水平

方案

≥99%

表单

powder

mp

280-282 °C (lit.)

储存温度

2-8°C

SMILES字符串

Nc1ncc2[nH]cnc2n1

InChI

1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)

InChI key

MWBWWFOAEOYUST-UHFFFAOYSA-N

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应用

αα2-氨基嘌呤已被用于抑制骨关节炎(OA)软骨细胞的真核起始因子2(eIF2)-磷酸化。
2-氨基嘌呤(2-AP)可用于双链RNA依赖性蛋白激酶、蛋白激酶R(PKR)的特异性抑制。

生化/生理作用

2-氨基嘌呤(2AP)是一种鸟苷和腺苷的类似物,可以与胞嘧啶和胸腺嘧啶碱基配对。它可用作核酸结构和动力学分析的荧光探针。2-氨基嘌呤(2-AP)可抑制双链RNA依赖性蛋白激酶蛋白激酶R(PKR)。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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