产品名称
2-氨基嘌呤, ≥99%
生物来源
synthetic
方案
≥99%
表单
powder
mp
280-282 °C (lit.)
储存温度
2-8°C
SMILES字符串
Nc1ncc2[nH]cnc2n1
InChI
1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
InChI key
MWBWWFOAEOYUST-UHFFFAOYSA-N
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应用
αα2-氨基嘌呤已被用于抑制骨关节炎(OA)软骨细胞的真核起始因子2(eIF2)-磷酸化。
2-氨基嘌呤(2-AP)可用于双链RNA依赖性蛋白激酶、蛋白激酶R(PKR)的特异性抑制。
生化/生理作用
2-氨基嘌呤(2AP)是一种鸟苷和腺苷的类似物,可以与胞嘧啶和胸腺嘧啶碱基配对。它可用作核酸结构和动力学分析的荧光探针。2-氨基嘌呤(2-AP)可抑制双链RNA依赖性蛋白激酶蛋白激酶R(PKR)。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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