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Merck
CN

A4626

1-乙酰基-2-苯肼

≥98%

别名:

N-Acetyl-N′-phenylhydrazine, acetylphenylhydrazine

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关于此项目

线性分子式:
CH3CONHNHC6H5
化学文摘社编号:
分子量:
150.18
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352127
EC Number:
204-055-3
MDL number:
Assay:
≥98%
Form:
(Powder with Chunk(s) or Crystals with Chunk(s))
Quality level:
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Quality Level

assay

≥98%

form

(Powder with Chunk(s) or Crystals with Chunk(s))

mp

128-131 °C (lit.)

SMILES string

CC(=O)NNc1ccccc1

InChI

1S/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)

InChI key

UICBCXONCUFSOI-UHFFFAOYSA-N

Application

用于造血系统研究的 1-乙酰基-2-苯肼 (AcPhHZ) 可与氧合血红蛋白反应形成自由基,可用于诱导溶血性贫血。

Biochem/physiol Actions

乙酰苯肼(1-Acetyl-2-phenylhydrazine,AcPhHZ) 是一种用于实验动物模型的血管肿瘤引发剂。

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

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H Ohno et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(2), 141-146 (1993-02-01)
DQ-2511, a new anti-ulcer drug, was administered to beagle dogs for 4 weeks to investigate the mechanism whereby this drug induced hemolytic anemia and its reversibility in comparison with beta-acetylphenylhydrazine. Hemolytic anemia accompanied by an increase in the number of
R Olinescu et al.
Research communications in chemical pathology and pharmacology, 84(1), 27-34 (1994-04-01)
Following the administration of phenylhydrazine, cadmium chloride and ethanol to rats there was a marked increase in the concentration of liver lipid peroxides and a sharp decline in GSH levels. The oxidative stress generated by the action of these toxic
Y Fujii et al.
Journal of electron microscopy, 46(6), 477-484 (1997-01-01)
A new 'tissue-stamp culture' method was developed for stamping proliferating erythroblasts of mouse spleens on collagen-coated coverslips after inducing haemolytic anaemia by administration of 1-acetyl-2-phenylhydrazine, and then adherent splenic cells were cultured for a few days. We could obtain many
M Boda et al.
Acta paediatrica Hungarica, 32(3), 241-255 (1992-01-01)
The erythrocyte glutathione metabolism of 11 children with acute celiac disease (CD), 11 children under gluten free diet with CD and 5 children with cow's milk allergy was compared to that of 11 children with nutritive iron deficiency and to
Simonetta Croci et al.
Anticancer research, 22(5), 2903-2906 (2003-01-18)
The end result of our research would be the development of a new diagnostic technique that could be used as a screening test, starting from a simple blood collection, a common procedure without any risk to the subject. Red blood

商品

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

全球贸易项目编号

货号GTIN
A4626-25G04061832860824
A4626-100G04061835542178

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