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Merck
CN

A4626

1-乙酰基-2-苯肼

≥98%

别名:

N-Acetyl-N′-phenylhydrazine, acetylphenylhydrazine

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关于此项目

线性分子式:
CH3CONHNHC6H5
化学文摘社编号:
分子量:
150.18
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352127
EC Number:
204-055-3
MDL number:
Assay:
≥98%
Form:
(Powder with Chunk(s) or Crystals with Chunk(s))
Quality level:
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产品名称

1-乙酰基-2-苯肼, ≥98%

InChI

1S/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)

InChI key

UICBCXONCUFSOI-UHFFFAOYSA-N

SMILES string

CC(=O)NNc1ccccc1

assay

≥98%

form

(Powder with Chunk(s) or Crystals with Chunk(s))

mp

128-131 °C (lit.)

Quality Level

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Biochem/physiol Actions

乙酰苯肼(1-Acetyl-2-phenylhydrazine,AcPhHZ) 是一种用于实验动物模型的血管肿瘤引发剂。

Application

用于造血系统研究的 1-乙酰基-2-苯肼 (AcPhHZ) 可与氧合血红蛋白反应形成自由基,可用于诱导溶血性贫血。

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

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H Ohno et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(2), 141-146 (1993-02-01)
DQ-2511, a new anti-ulcer drug, was administered to beagle dogs for 4 weeks to investigate the mechanism whereby this drug induced hemolytic anemia and its reversibility in comparison with beta-acetylphenylhydrazine. Hemolytic anemia accompanied by an increase in the number of
R Olinescu et al.
Research communications in chemical pathology and pharmacology, 84(1), 27-34 (1994-04-01)
Following the administration of phenylhydrazine, cadmium chloride and ethanol to rats there was a marked increase in the concentration of liver lipid peroxides and a sharp decline in GSH levels. The oxidative stress generated by the action of these toxic
Y Fujii et al.
Journal of electron microscopy, 46(6), 477-484 (1997-01-01)
A new 'tissue-stamp culture' method was developed for stamping proliferating erythroblasts of mouse spleens on collagen-coated coverslips after inducing haemolytic anaemia by administration of 1-acetyl-2-phenylhydrazine, and then adherent splenic cells were cultured for a few days. We could obtain many
P Caprari et al.
Biochemical medicine and metabolic biology, 45(1), 16-27 (1991-02-01)
After in vitro treatment of normal, glucose-6-phosphate dehydrogenase-deficient or pyruvate kinase-deficient human erythrocytes with three different oxidizing agents, the extent of lipid peroxidative degradation and the alterations of membrane proteins were evaluated. Exposure to tert-butylhydroperoxide induced, most markedly in G6PD-
R S Weinstein et al.
Journal of cell science, 94 ( Pt 3), 593-600 (1989-11-01)
An unusual form of red cells (called sequestrocytes) that circulate in the peripheral blood of patients with sickle cell anemia has been identified. In wetmount light microscopy preparations, sequestrocytes appear as massively vacuolated erythrocytes. We have shown by transmission electron

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