A4626
1-乙酰基-2-苯肼
≥98%
别名:
N-Acetyl-N′-phenylhydrazine, acetylphenylhydrazine
应用
用于造血系统研究的 1-乙酰基-2-苯肼 (AcPhHZ) 可与氧合血红蛋白反应形成自由基，可用于诱导溶血性贫血。
生化/生理作用
乙酰苯肼（1-Acetyl-2-phenylhydrazine，AcPhHZ) 是一种用于实验动物模型的血管肿瘤引发剂。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Y Fujii et al.
Journal of electron microscopy, 46(6), 477-484 (1997-01-01)
A new 'tissue-stamp culture' method was developed for stamping proliferating erythroblasts of mouse spleens on collagen-coated coverslips after inducing haemolytic anaemia by administration of 1-acetyl-2-phenylhydrazine, and then adherent splenic cells were cultured for a few days. We could obtain many
H Ohno et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(2), 141-146 (1993-02-01)
DQ-2511, a new anti-ulcer drug, was administered to beagle dogs for 4 weeks to investigate the mechanism whereby this drug induced hemolytic anemia and its reversibility in comparison with beta-acetylphenylhydrazine. Hemolytic anemia accompanied by an increase in the number of
R Olinescu et al.
Research communications in chemical pathology and pharmacology, 84(1), 27-34 (1994-04-01)
Following the administration of phenylhydrazine, cadmium chloride and ethanol to rats there was a marked increase in the concentration of liver lipid peroxides and a sharp decline in GSH levels. The oxidative stress generated by the action of these toxic
R S Weinstein et al.
Journal of cell science, 94 ( Pt 3), 593-600 (1989-11-01)
An unusual form of red cells (called sequestrocytes) that circulate in the peripheral blood of patients with sickle cell anemia has been identified. In wetmount light microscopy preparations, sequestrocytes appear as massively vacuolated erythrocytes. We have shown by transmission electron
S Croci et al.
Biochimica et biophysica acta, 1568(1), 99-104 (2001-12-04)
The oxidative action of acetylphenylhydrazine (APH) on red blood cells obtained from healthy donors and from patients with breast cancer has been investigated by Mössbauer spectroscopy. Whole blood was incubated with APH for different time periods and the Mössbauer spectra
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