A6850
壬二酰 PAF
10 mg/mL in ethanol
别名:
1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine, 1-O-Hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine, hexadecyl azelaoyl phosphatidylcholine
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关于此项目
经验公式（希尔记法）:
C33H66NO9P
分子量:
651.85
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
200-578-6
MDL number:
Form:
liquid
Quality level:
InChI key
ZDFOCDTXDPKJKA-WJOKGBTCSA-N
InChI
1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
form
liquid
concentration
10 mg/mL in ethanol
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
Azelaoyl PAF is a potent PPARγ agonist. Azelaoyl PAF has been used to investigate whether peroxisome proliferator-activated receptors gamma agonists could play a role in the treatment of Friedreich′s ataxia, a neurodegenerative disease due to frataxin deficiency.
Biochem/physiol Actions
Potent PPARγ agonist.
Features and Benefits
This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
57.2 °F - closed cup
flash_point_c
14 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Daniele Marmolino et al.
Cerebellum (London, England), 8(2), 98-103 (2008-12-24)
Friedreich's ataxia is a neurodegenerative disease due to frataxin deficiency, and thus, drugs increasing the frataxin amount are excellent candidates for therapy. By screening Gene Expression Omnibus profiles, we identified records showing a frataxin response to the peroxisome proliferator-activated receptors
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