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Merck
CN

A6883

Atropine methyl bromide

≥99% (TLC), powder

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关于此项目

经验公式(希尔记法):
C18H26NO3 · Br
化学文摘社编号:
分子量:
384.31
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
220-700-1
MDL number:
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InChI key

YBFLMRSYEWDJEJ-ZNHDNBJUSA-N

InChI

1S/C18H26NO3.BrH/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13;/h3-7,14-17,20H,8-12H2,1-2H3;1H/t14-,15+,16?,17?;

SMILES string

Br.C[N]1(C)[C@@H]2CC[C@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

assay

≥99% (TLC)

form

powder

color

white to off-white

solubility

H2O: 50 mg/mL

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Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist that does not cross the blood-brain barrier.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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Timothy A Yap et al.
Molecular cancer therapeutics, 10(2), 360-371 (2010-12-31)
AKT is frequently deregulated in cancer, making it an attractive anticancer drug target. CCT128930 is a novel ATP-competitive AKT inhibitor discovered using fragment- and structure-based approaches. It is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA
M M Knuepfer et al.
The American journal of physiology, 276(1 Pt 2), R103-R112 (1999-01-14)
It has been suggested that toxicity to cocaine is related to the relative rate of cocaine metabolism by cholinesterases and to activation of cholinergic receptors either directly or by reflex mechanisms. We examined these possibilities by altering cholinesterase activity and
G J Kirouac et al.
The American journal of physiology, 273(6 Pt 2), H2549-H2557 (1998-01-22)
Experiments were done in alpha-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect of L-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the
H Ohnuma et al.
Journal of the autonomic nervous system, 57(1-2), 43-48 (1996-02-05)
Hepatic glucoreceptor-vagal afferent inputs to the central nervous system and pancreatic vagal efferent stimuli are important for insulin secretion. In the present study, we examined the effect of intracerebroventricular (i.c.v.) injection of atropine methyl bromide (methylatropine) on the insulin response
Siew Kian Tai et al.
Hippocampus, 22(4), 914-925 (2011-05-05)
The vestibular system has been suggested to participate in spatial navigation, a function ascribed to the hippocampus. Vestibular stimulation during spatial navigation activates a hippocampal theta rhythm (4-10 Hz), which may enhance spatial processing and motor response. We hypothesize that

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