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Merck
CN

A7824

6-氨基己酸

synthetic (organic), ≥99%, antifibrinolytic agent, powder

别名:

ε-氨基己酸, 6-氨基己酸, EACA

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关于此项目

线性分子式:
H2N(CH2)5CO2H
化学文摘社编号:
分子量:
131.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
200-469-3
MDL number:
Beilstein/REAXYS Number:
906872
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产品名称

6-氨基己酸, BioUltra, ≥99%

InChI key

SLXKOJJOQWFEFD-UHFFFAOYSA-N

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

SMILES string

NCCCCCC(O)=O

biological source

synthetic (organic)

grade

biotech. grade

product line

BioUltra

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

207-209 °C (dec.) (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

room temp

Quality Level

Gene Information

human ... PLAT(5327), PLG(5340)
rat ... Ppm1a(24666)

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Biochem/physiol Actions

赖氨酸类似物。促进纤溶酶的快速解离,从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。
赖氨酸类似物。促进纤溶酶的快速解离,从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。据报道可抑制纤溶酶原与活化的血小板结合。 早期报告表明,它抑制补体系统第一成分的激活。结合羧肽酶 B并使其灭活。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

404.6 - 408.2 °F

flash_point_c

207 - 209 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Tijana Jovanovic-Talisman et al.
Methods in cell biology, 122, 379-393 (2014-05-27)
In vitro mimics of cellular machines have been recently engineered and utilized to investigate processes within cells. These devices can provide novel insights into biological mechanisms and have the potential to improve biotechnological processes such as separation. In particular, several
Robert A Gaultney et al.
PloS one, 8(9), e75643-e75643 (2013-10-03)
The causative agent of Lyme disease, Borrelia burgdorferi, codes for several known fibronectin-binding proteins. Fibronectin a common the target of diverse bacterial pathogens, and has been shown to be essential in allowing for the development of certain disease states. Another
Weining Bian et al.
Nature protocols, 4(10), 1522-1534 (2009-10-03)
This protocol describes a cell/hydrogel molding method for precise and reproducible biomimetic fabrication of three-dimensional (3D) muscle tissue architectures in vitro. Using a high aspect ratio soft lithography technique, we fabricate polydimethylsiloxane (PDMS) molds containing arrays of mesoscopic posts with
Alastair Khodabukus et al.
Toxicological sciences : an official journal of the Society of Toxicology, 176(1), 124-136 (2020-04-16)
Traditional serum biomarkers used to assess skeletal muscle damage, such as activity of creatine kinase (CK), lack tissue specificity and sensitivity, hindering early detection of drug-induced myopathies. Recently, a novel four-factor skeletal muscle injury panel (MIP) of biomarkers consisting of
Daniel C Turner et al.
Methods in molecular biology (Clifton, N.J.), 1889, 55-79 (2018-10-28)
The bioengineering of skeletal muscle tissue in-vitro has enabled researchers to more closely mimic the in-vivo skeletal muscle niche. The three-dimensional (3-D) structure of the tissue engineered systems employed to date enable the generation of highly aligned and differentiated myofibers

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