A9043
S-乙酰巯基乙酸 N-羟基琥珀酰亚胺酯
≥95% (TLC), powder
别名:
N-丁二酸S-乙酰基巯基乙二醇酯, N-琥珀酰亚胺基-S-乙酰硫基乙酸酯, S-乙酰硫基乙酸琥珀酰亚胺酯, SATA
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关于此项目
经验公式（希尔记法）:
C8H9NO5S
CAS Number:
分子量:
231.23
Beilstein:
7815491
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥95% (TLC)
表单
powder
溶解性
acetonitrile: 50 mg/mL
DMF: soluble
储存温度
−20°C
SMILES字符串
CC(=O)SCC(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
InChI key
FLCQLSRLQIPNLM-UHFFFAOYSA-N
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应用
伯胺的硫醇化试剂；在温和条件下可使硫醇去保护。通常在 pH 为 7.5 时引发耦合反应，通过酰胺键生成含伯胺的分子。在中性 pH 时可与 0.05M 羟胺发生去保护反应。用于制备酶免疫交联剂和半抗原载体分子偶联物。
其他说明
注意，与其他硫醇化试剂相比，对伯胺的酯偶合作用非常有效。此外，这种试剂可以中和伯胺的正电荷。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Magnus Bergkvist et al.
Methods in molecular biology (Clifton, N.J.), 751, 381-400 (2011-06-16)
Over the last decade, scanning probe microscopy (SPM) techniques, such as atomic force microscopy (AFM), have played an important role in a variety of biophysical research efforts. This straightforward technique has the capability to measure forces down to a few
A Delmas et al.
Bioconjugate chemistry, 3(1), 80-84 (1992-01-01)
We have previously shown that the carrier polytuftsin obtained by polycondensation of tuftsin, a naturally occurring macrophage activator, increases significantly the antibody response against a linked B-epitope. In the present work, we have studied the influence of different cross-linking reagents
Rükan Genç et al.
Analytical chemistry, 83(2), 563-570 (2010-12-16)
Liposomes are potential candidates as nanovesicles for the development of detection systems with improved sensitivity and detection limits, due to their capacity to encapsulate diverse types of signal enhancing molecules. An amperometric immunosensor exploiting enzyme encapsulating thermosensitive liposomes for the
J L Heeremans et al.
Biochimica et biophysica acta, 1117(3), 258-264 (1992-10-27)
The aim of this study was to find a suitable way of coupling the homing-device glu-plasminogen to the outside of liposomes. The described procedure is based on the reaction of thiol-groups introduced in the protein with thiol-reactive groups of the
Jing-Tang Lin et al.
PloS one, 7(4), e36086-e36086 (2012-05-09)
To develop a fluorescent ruthenium complex for biosensing, we synthesized a novel sulfhydryl-reactive compound, 4-bromophenanthroline bis-2,2'-dipyridine Ruthenium bis (hexafluorophosphate). The synthesized Ru(II) complex was crosslinked with thiol-modified protein G to form a universal reagent for fluorescent immunoassays. The resulting Ru(II)-protein
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