A9043
S-乙酰巯基乙酸 N-羟基琥珀酰亚胺酯
≥95% (TLC), powder
别名:
N-丁二酸S-乙酰基巯基乙二醇酯, N-琥珀酰亚胺基-S-乙酰硫基乙酸酯, S-乙酰硫基乙酸琥珀酰亚胺酯, SATA
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关于此项目
经验公式（希尔记法）:
C8H9NO5S
化学文摘社编号:
分子量:
231.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7815491
Assay:
≥95% (TLC)
Form:
powder
InChI
1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
SMILES string
CC(=O)SCC(=O)ON1C(=O)CCC1=O
InChI key
FLCQLSRLQIPNLM-UHFFFAOYSA-N
assay
≥95% (TLC)
form
powder
solubility
acetonitrile: 50 mg/mL, DMF: soluble
storage temp.
−20°C
Quality Level
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Application
伯胺的硫醇化试剂；在温和条件下可使硫醇去保护。通常在 pH 为 7.5 时引发耦合反应，通过酰胺键生成含伯胺的分子。在中性 pH 时可与 0.05M 羟胺发生去保护反应。用于制备酶免疫交联剂和半抗原载体分子偶联物。
Other Notes
注意，与其他硫醇化试剂相比，对伯胺的酯偶合作用非常有效。此外，这种试剂可以中和伯胺的正电荷。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Screening of monoclonal antibodies using antigens labeled with acetylcholinesterase.
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Over the last decade, scanning probe microscopy (SPM) techniques, such as atomic force microscopy (AFM), have played an important role in a variety of biophysical research efforts. This straightforward technique has the capability to measure forces down to a few
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The aim of this study was to find a suitable way of coupling the homing-device glu-plasminogen to the outside of liposomes. The described procedure is based on the reaction of thiol-groups introduced in the protein with thiol-reactive groups of the
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We have previously shown that the carrier polytuftsin obtained by polycondensation of tuftsin, a naturally occurring macrophage activator, increases significantly the antibody response against a linked B-epitope. In the present work, we have studied the influence of different cross-linking reagents
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The two coupling agents SPDP (N-succinimidyl-3-(2-pyridyldithio)propionate) and SATA (N-succinimidyl-S-acetylthioacetate) were compared in their efficiency and feasibility to couple monoclonal antibodies (Abs) via thioether linkage to liposomes functionalized by various lipophilic maleimide compounds like N-(3-maleimidopropionyl)-N2-palmitoyl-L-lysine methyl ester (MP-PL), N-(3-maleimidopropionyl)phosphatidylethanolamide (MP-PE), N6-(6-maleimidocaproyl)-N2-palmitoyl-L-lysine
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