A9295
4-Androsten-4-ol-3,17-dione acetate
别名:
4-Acetoxy-4-androstene-3,17-dione
表单
solid
运输
ambient
储存温度
2-8°C
SMILES字符串
CC(=O)OC1=C2CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
InChI
1S/C21H28O4/c1-12(22)25-19-16-5-4-13-14-6-7-18(24)21(14,3)10-8-15(13)20(16,2)11-9-17(19)23/h13-15H,4-11H2,1-3H3/t13-,14-,15-,20+,21-/m0/s1
InChI key
LRXSFNGKRCOHRS-VMRCMBGLSA-N
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
S A Daniel et al.
Canadian journal of physiology and pharmacology, 61(5), 507-511 (1983-05-01)
Androgens have been shown to enhance follicle-stimulating hormones (FSH) induced aromatase activity in cultured granulosa cells obtained from the ovaries of immature rats, however, aromatizable androgens are more effective than nonaromatizable androgens. The present study was designed to investigate the
Inhibition of estrogen biosynthesis and regression of mammary tumors by aromatase inhibitors.
A M Brodie et al.
Advances in experimental medicine and biology, 138, 179-190 (1981-01-01)
Effect of an aromatase inhibitor (4-acetoxy-4-androstene-3,17-dione) on the stimulatory action of luteinizing hormone on estradiol-17 beta synthesis by rat preovulatory follicles in vitro.
G Evans et al.
Biology of reproduction, 25(2), 290-294 (1981-09-01)
A M Brodie et al.
Steroids, 38(6), 693-702 (1981-12-01)
4-Hydroxy-4-androstene-3,17-dione (4-OHA) and 4-acetoxy-4-androstene-3,17-dione (4-AcA), in addition to being competitive inhibitors of aromatase, cause time-dependent, irreversible, loss of enzyme activity in both human placental and rat ovarian microsomes. In vivo, treatment of rats with 4-OHA also causes loss of ovarian
Recent advances in studies on estrogen biosynthesis.
A M Brodie
Journal of endocrinological investigation, 2(4), 445-460 (1979-10-01)
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