产品名称
Bone Morphogenetic Protein 2 human, Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
mol wt
26 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, tested
color
white
solubility
water: soluble 0.100 mL, clear, colorless
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... BMP2(650)
Biochem/physiol Actions
Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.
Physical form
Lyophilized from a 0.2 μm filtered buffered solution.
Analysis Note
The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
104.0 °F - closed cup
flash_point_c
40.0 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Lindsay A Bonsignore et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(7), 979-987 (2015-02-14)
The most important factor contributing to short-term and long-term success of cementless total joint arthroplasties is osseointegration. Osseointegration leads to a direct structural and functional connection between living bone and the surface of an implant. Surface contaminants may remain on
Thorsten Pfirrmann et al.
Human molecular genetics, 24(11), 3119-3132 (2015-02-26)
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye segments. Mosaic corneal degeneration, presenile cataract and secondary glaucoma are associated with XMC. Beside that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the
Ernst B Hunziker et al.
Tissue engineering. Part A, 21(13-14), 2089-2098 (2015-04-22)
The articular cartilage layer of synovial joints is commonly lesioned by trauma or by a degenerative joint disease. Attempts to repair the damage frequently involve the performance of autologous chondrocyte implantation (ACI). Healthy cartilage must be first removed from the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B1814-10UG | 04061833426487 |