C0662
6-羧基荧光素
~97% purity (HPLC), powder
别名:
6-FAM, 氟
产品名称
6-羧基荧光素, ≥96% (HPLC)
质量水平
方案
≥96% (HPLC)
表单
powder
技术
titration: suitable
颜色
dark yellow to dark orange
mp
>300 °C (lit.)
溶解性
0.1 M NaOH: 9.80-10.20 mg/mL, clear to slightly hazy, orange
λmax
492 nm at 0.1 N in NaOH
荧光
λex 492 nm; λem 517 nm (pH 8.0)
应用
diagnostic assay manufacturing
hematology
histology
储存温度
2-8°C
SMILES字符串
OC(=O)c1ccc2C(=O)OC3(c4ccc(O)cc4Oc5cc(O)ccc35)c2c1
InChI
1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25)
InChI key
BZTDTCNHAFUJOG-UHFFFAOYSA-N
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应用
6-羧基荧光素已用于精子细胞质膜完整性的检测。
荧光染料。
生化/生理作用
6-羧基荧光素二乙酸酯是一种膜渗透性化合物。可被细胞内酯酶水解，形成膜不可渗透的亮绿色荧光分子 6-羧基荧光素。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Andrew B Janowski et al.
mBio, 10(4) (2019-07-11)
Recent advances in unbiased pathogen discovery have implicated astroviruses as pathogens of the central nervous system (CNS) of mammals, including humans. However, the capacity of astroviruses to be cultured in CNS-derived cells in vitro has not been reported to date.
Przemysław Płociński et al.
Nature communications, 8(1), 1251-1251 (2017-11-02)
Prokaryotic Ligase D is a conserved DNA repair apparatus processing DNA double-strand breaks in stationary phase. An orthologous Ligase C (LigC) complex also co-exists in many bacterial species but its function is unknown. Here we show that the LigC complex
Bikash Malla et al.
Food and environmental virology, 11(3), 274-287 (2019-05-16)
Monitoring of environmental water is crucial to protecting humans and animals from possible health risks. Although numerous human-specific viral markers have been designed to track the presence of human fecal contamination in water, they lack adequate sensitivity and specificity in
Evgeny A Semchenko et al.
mBio, 10(4) (2019-07-11)
Neisseria gonorrhoeae is a significant threat to global health for which a vaccine and novel treatment options are urgently needed. Glycans expressed by human cells are commonly targeted by pathogens to facilitate interactions with the host, and thus characterization of
Stephanie Pfaender et al.
Hepatology (Baltimore, Md.), 61(2), 447-459 (2014-09-13)
Hepatitis C virus (HCV) has a very narrow species and tissue tropism and efficiently replicates only in humans and the chimpanzee. Recently, several studies identified close relatives to HCV in different animal species. Among these novel viruses, the nonprimate hepaciviruses
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