C0780
一水肌酸
suitable for cell culture
别名:
N-胺肉胺酸, α-甲胍乙酸
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关于此项目
线性分子式:
H2NC(=NH)N(CH3)CH2CO2H
化学文摘社编号:
分子量:
131.13
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-306-6
MDL number:
Beilstein/REAXYS Number:
907175
产品名称
一水肌酸, anhydrous
grade
anhydrous
Quality Level
form
powder
technique(s)
cell culture | mammalian: suitable
color
white
SMILES string
CN(CC(O)=O)C(N)=N
InChI
1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)
InChI key
CVSVTCORWBXHQV-UHFFFAOYSA-N
Application
肌酸（Cr）和磷酸肌酸（PCr）通过肌酸激酶的作用主要在骨骼肌组织中快速产生ATP。肌酸可用作研究其摄取机制和作用代谢的补充剂。
Biochem/physiol Actions
肌酸是一种含氮化合物，可充当 ATP 快速再生的高能量储存库。
肌酸是一种含氮化合物，可充当 ATP 快速再生的高能量储存库。大约 95% 的肌酸存在于骨骼肌中，主要为磷酸肌酸。肌酸可通过饮食摄入，也可由 L-精氨酸、甘氨酸和 L-蛋氨酸在肾脏和肝脏发生的多步骤反应中形成。肌酸随后被转运至肌肉组织。肌酸补充剂主要通过增加肌肉质量来增强运动成绩。肌酸还被研究用于神经肌肉疾病的治疗，可能有助于神经保护和改善细胞生物能量状态。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The Journal of clinical investigation, 124(11), 4915-4925 (2014-10-02)
Animal models suggest that acetylcarnitine production is essential for maintaining metabolic flexibility and insulin sensitivity. Because current methods to detect acetylcarnitine involve biopsy of the tissue of interest, noninvasive alternatives to measure acetylcarnitine concentrations could facilitate our understanding of its
Dan Atar et al.
European heart journal, 36(2), 112-119 (2014-09-03)
The MITOCARE study evaluated the efficacy and safety of TRO40303 for the reduction of reperfusion injury in patients undergoing revascularization for ST-elevation myocardial infarction (STEMI). Patients presenting with STEMI within 6 h of the onset of pain randomly received TRO40303
Subrata Patra et al.
Amino acids, 42(6), 2319-2330 (2011-07-20)
The creatine/creatine kinase (CK) system plays a key role in cellular energy buffering and transport. In vertebrates, CK has four isoforms expressed in a tissue-specific manner. In the process of creatine biosynthesis several other important metabolites are formed. The anticancer
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C0780-500G | 04061833452134 |
| C0780-100G | 04061833452103 |
| C0780-10MG | 04061833452127 |
| C0780-50G | 04061833452172 |