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Merck
CN

C197

Sigma-Aldrich

8-(3-Chlorostyryl)caffeine

≥98% (HPLC), solid

别名:

1,3,7-Trimethyl-8-(3-chlorostyryl)xanthine, CSC

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About This Item

经验公式(希尔记法):
C16H15ClN4O2
CAS Number:
分子量:
330.77
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

solid

颜色

white

溶解性

DMSO: >5 mg/mL

储存温度

−20°C

SMILES字符串

[H]\C(=C(\[H])c1nc2C(=O)N(C)C(=O)N(C)c2n1C)c3cccc(Cl)c3

InChI

1S/C16H15ClN4O2/c1-19-12(8-7-10-5-4-6-11(17)9-10)18-13-14(19)20(2)16(23)21(3)15(13)22/h4-9H,1-3H3/b8-7+

InChI key

MHYRUZOJQQLLQS-BQYQJAHWSA-N

基因信息

应用

8-(3-Chlorostyryl)caffeine has been used as an adenosine A2A receptor antagonist:
  • to study its effects on levodopa (L-DOPA)-induced dopamine (DA) release in rat striatum
  • to study its effect on the nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) activity in macrophages
  • to determine its effects on human umbilical vein endothelial cells (HUVECs)

生化/生理作用

8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist and monoamine oxidase B (MAO B) inhibitor.

特点和优势

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Photosensitive, store in the dark

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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