一般描述
酪蛋白是牛奶中主要的磷酸化蛋白质，约占牛奶总蛋白质含量的80%。牛奶由四类酪蛋白组成，如αS1、αS2、β和κ。酪蛋白以胶束形式存在于牛奶中。
应用
牛奶中的酪蛋白-异硫氰酸荧光素已被用于：
- 作为对拟南芥细胞中的蛋白酶进行半定量分析的底物
- 测定分泌的LasB（弹性蛋白酶）、碱性蛋白酶和蛋白酶IV的酪蛋白水解活性
- 测定化脓性链球菌细胞中SpeB（半胱氨酸蛋白酶）的活性
高度灵敏的蛋白酶底物
生化/生理作用
酪蛋白胶束系统可参与到乳腺病理性钙化的预防中。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
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历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Laura Reinhardt et al.
mBio, 13(6), e0141322-e0141322 (2022-10-27)
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Mark F Mabanglo et al.
Communications biology, 2, 410-410 (2019-11-23)
Bacterial ClpP is a highly conserved, cylindrical, self-compartmentalizing serine protease required for maintaining cellular proteostasis. Small molecule acyldepsipeptides (ADEPs) and activators of self-compartmentalized proteases 1 (ACP1s) cause dysregulation and activation of ClpP, leading to bacterial cell death, highlighting their potential
Invited review: Understanding the behavior of caseins in milk concentrates
Corredig M, et al.
Journal of Dairy Science, 102(6), 4772-4782 (2019)
Thomas S Murray et al.
Journal of medical microbiology, 59(Pt 5), 511-520 (2010-01-23)
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen capable of acutely infecting or persistently colonizing susceptible hosts. P. aeruginosa colonizes surfaces in vitro by either biofilm formation or swarming motility. The choice of behaviour is influenced by the physical properties of
An Arabidopsis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis
Ge X, et al.
EMBO Reports, 6(3), 282-288 (2005)
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