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Merck
CN

C6143

Sigma-Aldrich

氯己定 二乙酸盐 水合物

bis(biguanide) antimicrobial

别名:

1,6-双（N5-[对氯苯基]-N1-双胍）己烷；1,1′-六亚甲基双（5-[对氯苯基] 双胍）

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关于此项目

经验公式（希尔记法）:
C22H30Cl2N10 · 2C2H4O2 · xH2O
CAS Number:
206986-79-0
分子量:
625.55 (anhydrous basis)
EC 号:
200-302-4
MDL编号:
MFCD00012532
UNSPSC代码:
51102829
PubChem化学物质编号:
24892838
NACRES:
NA.85

主要文件

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质量水平

200

表单

powder

CMC

0.01% (25°C)(w/v)

溶解性

ethanol: 50 mg/mL

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell membrane | interferes

储存温度

room temp

SMILES字符串

ClC1=CC=C(NC(NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N)=N)C=C1.OC(C)=O.OC(C)=O

InChI

1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)

InChI key

WDRFFJWBUDTUCA-UHFFFAOYSA-N

相关类别

应用

可用于研究双（双胍）分子破坏膜的作用机制。

生化/生理作用

氯己定是一种阳离子广谱抗菌药物，属于双（双胍类）家族。其作用机制涉及外层细菌膜的不稳定。对革兰阳性菌和革兰阴性菌均有效。氯己定主要作为局部抗菌剂/消毒剂用于伤口愈合、导管插入部位、各种牙科应用和外科擦洗剂。

其他说明

将容器密闭保存在干燥和通风良好的地方。在干燥处保存。

免责声明

本品不可用作全球生物杀灭剂法规监管的生物杀灭剂，包括但不限于：美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2

靶器官

Liver,Teeth

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF3830V
WXBF5142V
0000400156
0000414826
0000400156

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