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Merck
CN

C6542

Monoclonal Anti-Caldesmon antibody produced in mouse

clone CALD-5, ascites fluid

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UNSPSC Code:
12352203
MDL number:
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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

CALD-5, monoclonal

contains

15 mM sodium azide

species reactivity

human, chicken

technique(s)

indirect immunofluorescence: suitable using frozen human tissue sections, microarray: suitable, western blot: 1:100 using chicken gizzard extract

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CALD1(800)

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Immunogen

caldesmon from turkey gizzard

Biochem/physiol Actions

The antibody localizes the high molecular weight form of caldesmon in chicken or turkey gizzard and the low molecular weight form of caldesmon in chicken fibroblasts by immunoblotting. CALD-5 localizes both the high and low molecular weight caldesmons in cultured human smooth muscle cells. The antibody reacts with epitopes located on the N-terminal, non-calmodulin-binding part of caldesmon.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lot/Batch Number

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W Durand-Arczynska et al.
Histochemistry, 100(6), 465-471 (1993-12-01)
Calponin and caldesmon are two proteins considered to play a regulatory role in smooth muscle contraction, which have never previously been found to be expressed in subcultured cells. In the present study, immunocytochemistry and immunoblotting were performed to identify these
Javier Kattan et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 230(1), 34-43 (2004-04-27)
To study the formation of the coronary vessels in the developing avian heart, we stained developmentally staged quail hearts with the endothelial specific antibody QH-1. QH-1 reacted with individual cells in the proepicardial organ in Hamburger and Hamilton stage (HH)
W Rozek et al.
Polish journal of veterinary sciences, 16(4), 663-669 (2013-01-01)
Changes in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of

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