生物来源
mouse
偶联物
CY3 conjugate
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
9E10, monoclonal
表单
buffered aqueous solution
种属反应性
human
技术
direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue
UniProt登记号
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... MYC(4609)
正在寻找类似产品? 访问 产品对比指南
一般描述
Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa.
免疫原
人p62c-Myc蛋白的合成肽。
应用
Monoclonal Anti-c-MycCy3™ antibody produced in mouse has been used in:
- western blotting
- immunocytochemistry
- Immunofluorescence
生化/生理作用
The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation.
外形
Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.
法律信息
Cy3 is a trademark of Cytiva
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Karen Marie Juul Sørensen et al.
BMC cancer, 17(1), 19-19 (2017-01-07)
One of the hallmarks of cancer is an altered energy metabolism, and here, mitochondria play a central role. Previous studies have indicated that some mitochondrial ribosomal proteins change their expression patterns upon transformation. In this study, we have used the
Nicolina Cristina Sorrentino et al.
EMBO molecular medicine, 5(5), 675-690 (2013-04-10)
Mucopolysaccharidoses type IIIA (MPS-IIIA) is a neurodegenerative lysosomal storage disorder (LSD) caused by inherited defects of the sulphamidase gene. Here, we used a systemic gene transfer approach to demonstrate the therapeutic efficacy of a chimeric sulphamidase, which was engineered by
Genetic alteration of chromosome 8 is a common feature of human mammary epithelial cell lines transformed in vitro with benzo [a] pyrene
Caruso JA, et al.
Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis, 473(1), 85-99 (2001)
Meirav Noach-Hirsh et al.
Molecular & cellular proteomics : MCP, 14(10), 2824-2832 (2015-08-16)
Protein post-translational modifications mediate dynamic cellular processes with broad implications in human disease pathogenesis. There is a large demand for high-throughput technologies supporting post-translational modifications research, and both mass spectrometry and protein arrays have been successfully utilized for this purpose.
Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms
Shimazu S, et al.
Cancer Science, 102(11), 2097-2102 (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持