生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
克隆
K8.12, monoclonal
包含
15 mM sodium azide
种属反应性
bovine, human
技术
indirect immunofluorescence: 1:20 using frozen human tissue sections
microarray: suitable
western blot: suitable
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
基因信息
human ... KRT13(3860), KRT15(3866), KRT16(3868)
免疫原
bovine epidermal keratin
生化/生理作用
Reacts with cytokeratins 13, 15 and 16. Labels non-keratinizing squamous epithelium, the basal layer of pseudostratified epithelium and transitional epithelium. Does not react with normal epidermis or most simple epithelial cells. Reacts with all squamous cell carcinomas tested, but not with adenocarcinomas. A subset of breast carcinoma is detected with this antibody.
法规信息
新产品
此项目有
Piet E J van Erp
Methods in molecular biology (Clifton, N.J.), 289, 239-250 (2004-10-27)
Our knowledge of the etiology and pathogenesis of skin diseases characterized by abnormal growth is relatively limited. Even more important, still very little is known of how epidermopoeisis is controlled in normal epidermis. There is no cure for skin diseases
R H Wetzels et al.
The American journal of pathology, 138(3), 751-763 (1991-03-01)
In normal breast tissue and in noninvasive breast carcinomas, various keratin-14 antibodies were reactive predominantly with the basal/myoepithelial cell layer, although mainly in terminal and larger ducts luminal cells sometimes also were stained. A similar reaction pattern was found with
A Tsubura et al.
Histopathology, 18(6), 517-522 (1991-06-01)
The immunohistochemical reactivities of 69 cases of breast carcinoma were examined on methacarn-fixed, paraffin-embedded sections using eight different monoclonal antibodies which recognize one or a few keratin polypeptides. In the normal breast, the monoclonal antibodies RPN1162, RPN1165 and AE1 stained
I Moll et al.
Archives of dermatological research, 283(5), 300-309 (1991-01-01)
Human eccrine sweat gland ducts and benign and malignant eccrine poromas were studied for the expression of various cytokeratins (CK) and vimentin by applying immunoperoxidase and immunofluorescence microscopy to frozen or paraffin-embedded sections, and using two-dimensional gel electrophoresis and immunoblotting.
O Gigi-Leitner et al.
Differentiation; research in biological diversity, 31(3), 191-205 (1986-01-01)
The expression of cytokeratin polypeptides in squamous metaplasia of the human uterine cervix was investigated by immunocytochemical labeling with polypeptide-specific antibodies against cytokeratins. Immunofluorescence microscopic examination of cervical tissues using various monoclonal antibodies indicated that squamous cervical metaplasia expresses a
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持