C8276
6-氯嘌呤核苷
别名:
6-氯嘌呤-9-β-D-呋喃核糖苷
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H11ClN4O4
化学文摘社编号:
分子量:
286.67
EC Number:
226-438-4
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
40573
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Solubility:
DMF: 49-51 mg/mL, clear, colorless to faintly yellow
Storage temp.:
−20°C
InChI key
XHRJGHCQQPETRH-KQYNXXCUSA-N
InChI
1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(Cl)ncnc23
assay
≥98% (HPLC)
form
powder
mp
158-162 °C (dec.) (lit.)
solubility
DMF: 49-51 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
Application
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
B A Iuodka et al.
Biokhimiia (Moscow, Russia), 58(6), 857-865 (1993-06-01)
The NTP binding site of bacteriophage T4 RNA-ligase (EC 6.5.1.3) was studied using several ATP analogs modified in the purine moiety of the nucleotide at positions 1, 2, 6 and 8: adenosine-N'-oxide 5'-triphosphate (I), 6-chloropurine riboside 5'-triphosphate (II), 6-mercaptopurine riboside
L S Singh et al.
Molecular and cellular biochemistry, 204(1-2), 127-134 (2000-03-16)
Adenosine deaminase (ADA) was isolated from small intestine of mice and purified to utmost homogeneity. SDS-PAGE of purified ADA gave a molecular weight of 41 kDa. Western blot analyses gave a single reactive band at 41 kDa and the other
R M Richardson et al.
Biochimica et biophysica acta, 953(1), 70-78 (1988-03-02)
When the reaction of bovine pancreatic ribonuclease A with 6-chloropurine riboside 5'-monophosphate was carried out in the presence of several natural mononucleotides, a decrease of 25-75% was found in the amount of the reaction product derivative II (the main product
Cintia W Rivero et al.
Bioorganic & medicinal chemistry letters, 22(19), 6059-6062 (2012-09-11)
This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2'-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stearothermophilus CECT 43 with a conversion of 90% and 68%, respectively. Furthermore, the selected microorganism was satisfactorily
Shigetada Kozai et al.
Nucleosides, nucleotides & nucleic acids, 22(5-8), 779-781 (2003-10-21)
A new method to introduce a benzyl group onto the 2'-OH of purine ribonucleoside is described. Thus, 6-chloropurine 3'-O-benzoylriboside and its 5'-O-trityl congener were condensed with benzyl alcohol using the Mitsunobu reaction to give the 2'-O-benzyl derivative. The yields were
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持