C8417
N-(2-氯乙基)-N-乙基-2-溴苄胺 盐酸盐
≥98% (TLC), solid, adrenergic neurotoxin
别名:
DSP-4, N-乙基-N-(2-氯乙基)-2-溴苄胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C11H15BrClN · HCl
化学文摘社编号:
分子量:
313.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Beilstein/REAXYS Number:
4020910
产品名称
N-(2-氯乙基)-N-乙基-2-溴苄胺 盐酸盐, ≥98%, solid
Quality Level
assay
≥98%
form
solid
color
white
solubility
H2O: 48 mg/mL, 0.1 M NaOH: 7 mg/mL, ethanol: soluble
SMILES string
Cl[H].CCN(CCCl)Cc1ccccc1Br
InChI
1S/C11H15BrClN.ClH/c1-2-14(8-7-13)9-10-5-3-4-6-11(10)12;/h3-6H,2,7-9H2,1H3;1H
InChI key
NDDRNRRNYOULND-UHFFFAOYSA-N
Biochem/physiol Actions
肾上腺素能神经毒素诱导中枢和外周去甲肾上腺素能神经末梢的急性和相对选择性变性。
Preparation Note
乙醇、水或0.1N NaOH溶液应在临用前配制。
Disclaimer
吸湿的。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
T Skrebuhhova et al.
Methods and findings in experimental and clinical pharmacology, 21(7), 483-490 (1999-11-02)
[3H]-Ketanserin binding in rat neocortex (frontal and cerebral cortex) after 3-week treatment with desipramine (10 mg/kg) and citalopram (5 mg/kg) in vehicle-, DSP-4- (50 mg/kg) and p-CPA- (350 mg/kg before the beginning of experiments and once per week on the
Delphine Guérin et al.
Behavioral neuroscience, 122(4), 816-826 (2008-08-30)
Noradrenergic projections from the locus coeruleus (LC) project to the olfactory bulb (OB), a cortical structure implicated in odor learning and perceptual differentiation among similar odorants. The authors tested the role of OB noradrenaline (NA) in short-term olfactory memory using
Yun-Fei Lü et al.
Frontiers in neural circuits, 11, 66-66 (2017-10-06)
Empathy for pain (vicariously felt pain), an ability to feel, recognize, understand and share the painful emotions of others, has been gradually accepted to be a common identity in both humans and rodents, however, the underlying neural and molecular mechanisms
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C8417-100MG | 04061833522295 |
| C8417-250MG | 04061832090009 |