表单
powder or crystals
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
enzyme | inhibits
储存温度
2-8°C
应用
克拉维酸用作细菌 β-内酰胺酶的抑制剂。它是由棒状链霉菌发酵产生的。单独使用时，其抗菌活性较弱，但与阿莫西林联用时，则具有很高的活性。与阿莫西林一起，可用于治疗由金黄色葡萄球菌、脆弱拟杆菌、流感嗜血杆菌和大肠杆菌引起的感染。它已用于治疗儿童急性细菌性鼻窦炎和慢性腺扁桃体肥大。
生化/生理作用
克拉维酸是一种 β-内酰胺酶抑制剂，常用于增强阿莫西林的抗菌活性。
克拉维酸是一种与青霉素有关的 β-内酰胺抗生素。克拉维酸竞争性地且不可逆地抑制多种 β-内酰胺酶，β-内酰胺酶广泛存在于对青霉素和头孢菌素具有抗性的微生物中。克拉维酸也是中枢神经系统的调节剂。它增强了 PC12 和 SH-SY5Y 细胞中的多巴胺释放，而不会影响多巴胺的合成。
其他说明
克拉维酸钾和纤维素的混合物
将容器密闭存放在干燥通风处。存放期间切勿让产品与水接触。储存等级（TRGS 510）：易燃固体危险品。
警示用语：
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
补充剂危害
储存分类代码
13 - Non Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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B Rossi et al.
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