D2629
6-（二甲氨基）嘌呤
≥98%, synthetic (organic), powder
别名:
6-DMAP, N6,N6-二甲腺嘌呤
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关于此项目
经验公式（希尔记法）:
C7H9N5
化学文摘社编号:
分子量:
163.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
213-344-3
MDL number:
Beilstein/REAXYS Number:
7634
Assay:
≥98%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to hazy, colorless to light yellow
Storage temp.:
−20°C
产品名称
6-（二甲氨基）嘌呤, ≥98%
biological source
synthetic (organic)
Quality Level
assay
≥98%
form
powder
mp
259-262 °C (lit.)
solubility
water: 50 mg/mL, clear to hazy, colorless to light yellow
storage temp.
−20°C
SMILES string
CN(C)c1ncnc2[nH]cnc12
InChI
1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
InChI key
BVIAOQMSVZHOJM-UHFFFAOYSA-N
General description
6-二甲氨基嘌呤(6-DMAP)是一种嘌呤类代谢物，含有2个缩合杂环及与腺嘌呤的嘌呤氨基（环外氨基）连接的2个甲基。
Application
6-二甲氨基嘌呤已用于：
- 作为GR-1 aa培养基（牛培养基）补充剂，用于牛卵母细胞的孤雌激活，以研究其对胚胎发育的影响
- 核移植胚胎生产中的激活步骤
- 作为HCR2aa培养基补充剂，用于激活通过异种体细胞核移植(iSCNT)技术获得的异种胚胎
Biochem/physiol Actions
6-二甲氨基嘌呤(6-DMAP)是一种蛋白激酶和细胞周期蛋白依赖性激酶抑制剂。它是一种次生代谢产物，介导RNA修饰。6-DMAP是一种强效的细胞质分裂抑制剂，用于孤雌生殖和减数分裂研究。它也可用于促进哺乳动物卵母细胞的前核形成。根据飞秒荧光上转换光谱技术，6-DMAP是一种双荧光(dual fluorescence)分子。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The aim of the present investigation was to study the effect of oocyte selection on the efficiency of bovine nuclear transfer in terms of increased blastocyst production. For this purpose, prior to in vitro maturation (IVM), oocytes were selected for
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D2629-100MG | 04061838357700 |
| D2629-250MG | 04061833562475 |
| D2629-500MG | 04061833562482 |
| D2629-1G | 04061833562468 |
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