D9302
双醋瑞因
≥95% (HPLC)
别名:
1,8-二乙酰氧基-3-羧基蒽醌
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关于此项目
经验公式（希尔记法）:
C19H12O8
化学文摘社编号:
分子量:
368.29
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
237-310-2
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
assay
≥95% (HPLC)
form
powder
SMILES string
CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(C)=O)c3C(=O)c12)C(O)=O
InChI
1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
InChI key
TYNLGDBUJLVSMA-UHFFFAOYSA-N
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Biochem/physiol Actions
双醋瑞因是白介素-1B（IL-1B）产生的抑制剂。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
E M Bartels et al.
Osteoarthritis and cartilage, 18(3), 289-296 (2009-10-28)
To estimate the efficacy and safety of diacerein as a pain-reducing agent in the treatment of osteoarthritis (OA), using meta-analysis of published randomized placebo-controlled trials (RCTs). Systematic searches of the bibliographic databases Medline, Embase, Cinahl, Chemical Abstracts, Cochrane and Web
Vinícius Maria Gadotti et al.
Pharmacology, biochemistry, and behavior, 102(4), 549-554 (2012-07-04)
The present study evaluated the antinociceptive effect of the pro-inflammatory cytokines inhibitor diacerein in mice and its possible mechanism of action. The antinociception produced by diacerein was tested at different sites of action, moreover selective antagonists or agonists were used
Achint Jain et al.
Journal of biomedical nanotechnology, 9(5), 891-900 (2013-06-28)
Osteoarthritis is the most common, multi component joint disease mainly characterized by destruction of articular cartilage which leads up to subchondral bone. Current treatment by NSAID's gives only symptomatic relief but semi-synthetic anthraquinone diacerein is novel chondroprotective agent intended for
Olivier Bruyère et al.
BMC musculoskeletal disorders, 9, 165-165 (2008-12-18)
Symptomatic slow-acting drugs (SYSADOA) have been largely studied over the last decade. The objective of this study is to prepare a document providing recommendations for the use of SYSADOA in osteoarthritis (OA). The following interventions were taken into consideration: avocado/soybean
Juliana Saibt Martins Pasin et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 59(3), 189-196 (2009-09-05)
To investigate the effect of diacerein, an anti-inflammatory drug, on body temperature and protocols of fever induction in male Wistar rats. The effect of diacerein (5.0 mg/kg, s.c.) on rectal temperature (T (R)) changes induced by Baker's yeast (0.135 g/kg
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D9302-50MG | 04061833590591 |
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