D9761
6-脱氧-D-葡萄糖
别名:
D-异鼠李糖, Epifucose, Quinovose
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关于此项目
经验公式（希尔记法）:
C6H12O5
化学文摘社编号:
分子量:
164.16
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
231-622-2
Beilstein/REAXYS Number:
1723317
MDL number:
Quality Level
grade
Molecular Biology
assay
≥98% (TLC)
form
powder
storage temp.
−20°C
SMILES string
C[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5-,6?/m1/s1
InChI key
SHZGCJCMOBCMKK-GASJEMHNSA-N
General description
6-脱氧-D-葡萄糖是D-葡萄糖（右旋葡萄糖）的一种结构同源物和稳定的类似物。它在碳6位上缺少羟基。它也是甘露糖的类似物。
Application
6-脱氧-D-葡萄糖已被用作圆二色性测量中的标准品。它也作为糖用于孵育经饥饿处理的双歧杆菌HMX44A.atg1-1细胞，从而用于显微镜研究。
Biochem/physiol Actions
2-脱氧-D-葡萄糖（2-DG）在研究葡萄糖的生物学功能中可用作糖酵解抑制剂。它不可被代谢，会引发内质网的应激，因而可阻止癌细胞中碳水化合物的代谢。它具有靶向抗化学性缺氧癌细胞的治疗潜力。2-DG可通过取代甘露糖终止 N-连接糖基化。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
A J Fry et al.
Molecular and biochemical parasitology, 60(1), 9-18 (1993-07-01)
Kinetic parameters for entry of D-fructose into Trypanosoma brucei brucei have been determined. The net uptake of D-fructose was found to be rapid and occurred at a rate which was comparable with that observed for uptake of D-glucose. The Km
D Granot et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(13), 5724-5728 (1991-07-01)
Nutrients play a critical role in the decision to initiate a new cell cycle. Addition of nutrients to arrested cells such as stationary-phase cells and spores induces them to begin growth. We have analyzed the nutrients required to induce early
Mark W Ruszczycky et al.
Journal of the American Chemical Society, 133(19), 7292-7295 (2011-04-26)
DesII, a radical S-adenosyl-l-methionine (SAM) enzyme from Streptomyces venezuelae, catalyzes the deamination of TDP-4-amino-4,6-dideoxy-D-glucose to TDP-3-keto-4,6-dideoxy-D-glucose in the desosamine biosynthetic pathway. DesII can also catalyze the dehydrogenation of TDP-D-quinovose to the corresponding 3-keto sugar. Similar to other radical SAM enzymes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D9761-100MG | 04061833591093 |
| D9761-250MG | 04061833076330 |