E0377
D-赤藓糖-4-磷酸酯 钠盐
≥50% (TLC)
别名:
4-磷酸-D-赤藓糖 钠盐
质量水平
方案
≥50% (TLC)
表单
powder
颜色
white to off-white
溶解性
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
−20°C
SMILES字符串
[Na+].[H]C(=O)[C@H](O)[C@H](O)COP(O)([O-])=O
InChI
1S/C4H9O7P.Na/c5-1-3(6)4(7)2-11-12(8,9)10;/h1,3-4,6-7H,2H2,(H2,8,9,10);/q;+1/p-1/t3-,4+;/m0./s1
InChI key
KKDBADMPNGAKHM-RFKZQXLXSA-M
正在寻找类似产品? 访问 产品对比指南
应用
D-赤藓糖-4-磷酸(E4P)可作为底物，用于识别、区分和鉴定2-酮基-3-脱氧-6-磷酸半乳糖酸(KDPGal)醛缩酶和3-脱氧-D-阿拉伯-庚酮酸7-磷酸(DAH7P)合成酶，这两种酶用于启动微生物和植物中的莽草酸途径。可作为底物识别、区分和鉴定甘油醛-3-磷酸脱氢酶(GAPDH)，这种酶参与致病微生物的表面抗原和毒力因子形成。 PLP（吡哆醛5′-磷酸）合成酶复合物负责从头合成恶性疟原虫中的维生素B6，在疟疾研究中，E4P可作为该复合物PfPdx1组分的抑制剂。
生化/生理作用
D-赤藓糖-4-磷酸作为中间产物参与磷酸戊糖途径，以及苯丙氨酸、酪氨酸、色氨酸生物合成与维生素B6代谢。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
涉药品监管产品
此项目有
Ingrid B Müller et al.
PloS one, 4(2), e4406-e4406 (2009-02-07)
The human malaria parasite Plasmodium falciparum is able to synthesize de novo pyridoxal 5-phosphate (PLP), a crucial cofactor, during erythrocytic schizogony. However, the parasite possesses additionally a pyridoxine/pyridoxal kinase (PdxK) to activate B6 vitamers salvaged from the host. We describe
J Bongaerts et al.
Metabolic engineering, 3(4), 289-300 (2001-10-26)
Metabolic engineering to design and construct microorganisms suitable for the production of aromatic amino acids and derivatives thereof requires control of a complicated network of metabolic reactions that partly act in parallel and frequently are in rapid equilibrium. Engineering the
David Tran et al.
Bioorganic & medicinal chemistry letters, 21(22), 6838-6841 (2011-10-08)
3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) synthase catalyses the first step of the shikimate pathway, which is responsible for the biosynthesis of aromatic amino acids in microorganisms and plants. This enzyme catalyses an aldol reaction between phosphoenolpyruvate and D-erythrose 4-phosphate to generate DAH7P.
Scott R Walker et al.
Bioorganic & medicinal chemistry letters, 21(17), 5092-5097 (2011-04-16)
3-Deoxy-d-arabino-heptulosonate 7-phosphate (DAH7P) synthase catalyses the first step of the shikimate pathway for the biosynthesis of aromatic compounds. Enzymes of this pathway have been identified as potential targets for drug design. The reaction catalysed by DAH7P synthase is an aldol
Bouchra Elkhalfi et al.
Protein expression and purification, 89(2), 146-155 (2013-03-20)
The gammaproteobacterium Pseudomonas syringae pv. tomato DC3000 is the causal agent of bacterial speck, a common disease of tomato. The mode of infection of this pathogen is not well understood, but according to molecular biological, genomic and proteomic data it
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持