E4267
9-乙基鸟嘌呤
别名:
2-氨基-9-乙基-6-羟基嘌呤, 6-氨基-9-乙基-2-羟基嘌呤
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选择尺寸
关于此项目
经验公式（希尔记法）:
C7H9N5O
化学文摘社编号:
分子量:
179.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Application
9-Ethylguanine (9-EtG) is used as a DNA model base for a variety of physical chemical studies of organometallic complexes.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Amanda P Neves et al.
Journal of inorganic biochemistry, 119, 54-64 (2012-11-29)
Several chlorido and amino Pt(2+) complexes of 2-hydroxy-3-(aminomethyl)-1,4-naphthoquinone Mannich bases HL exhibiting moderate to high cytotoxicity against cancer cell lines were studied in order to investigate their modes of DNA binding, in vitro DNA strand breaks, mechanism of topoisomerase (Topo
Zhe Liu et al.
Inorganic chemistry, 50(12), 5777-5783 (2011-05-31)
Replacing the N,N-chelating ligand 2,2'-bipyridine (bpy) in the Ir(III) pentamethylcyclopentadienyl (Cp*) complex [(η(5)-C(5)Me(5))Ir(bpy)Cl](+) (1) with the C,N-chelating ligand 2-phenylpyridine (phpy) to give [(η(5)-C(5)Me(5))Ir(phpy)Cl] (2) switches on cytotoxicity toward A2780 human ovarian cancer cells (IC(50) values of >100 μM for 1
Anna F A Peacock et al.
Journal of the American Chemical Society, 129(11), 3348-3357 (2007-02-27)
Potential biological and medical applications of organometallic complexes are hampered by a lack of knowledge of their aqueous solution chemistry. We show that the hydrolytic and aqueous solution chemistry of half-sandwich OsII arene complexes of the type [(eta6-arene)Os(XY)Cl] can be
Haimei Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(25), 14623-14628 (2003-12-06)
Organometallic chemistry offers novel concepts in structural diversity and molecular recognition that can be used in drug design. Here, we consider DNA recognition by eta 6-arene Ru(II) anticancer complexes by an induced-fit mechanism. The stereochemistry of the dinuclear complex [((eta
Anna C G Hotze et al.
Inorganic chemistry, 43(16), 4935-4943 (2004-08-03)
The striking difference in cytotoxic activity between the inactive cis-[Ru(bpy)(2)Cl(2)] and the recently reported highly cytotoxic alpha-[Ru(azpy)(2)Cl(2)] (alpha indicating the isomer in which the coordinating Cl atoms, pyridine nitrogens, and azo nitrogens are in mutual cis, trans, cis orientation) encouraged
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