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Merck
CN

E4267

Sigma-Aldrich

9-乙基鸟嘌呤

别名:

2-氨基-9-乙基-6-羟基嘌呤, 6-氨基-9-乙基-2-羟基嘌呤

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关于此项目

经验公式(希尔记法):
C7H9N5O
化学文摘社编号:
分子量:
179.18
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
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方案

≥98%

质量水平

表单

powder

溶解性

1 M NaOH: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

储存温度

2-8°C

SMILES字符串

CCn1cnc2C(=O)N=C(N)Nc12

InChI

1S/C7H9N5O/c1-2-12-3-9-4-5(12)10-7(8)11-6(4)13/h3H,2H2,1H3,(H3,8,10,11,13)

InChI key

WDOYBEPLTCFIRQ-UHFFFAOYSA-N

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应用

9-Ethylguanine (9-EtG) is used as a DNA model base for a variety of physical chemical studies of organometallic complexes.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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Ganna V Kalayda et al.
Journal of medicinal chemistry, 48(16), 5191-5202 (2005-08-05)
The dinuclear platinum complexes with aliphatic diamines [{cis-Pt(NH(3))(2)Cl}(2)(mu-H(2)N(CH(2))(6)NH(2))](NO(3))(2) (1,1/c,c) and [{trans-Pt(NH(3))(2)Cl}(2)(mu-H(2)N(CH(2))(4)NH(2))](NO(3))(2) (1,1/t,t), which are known to be highly active in vitro against several cancer cell lines, have been modified with a fluorogenic reporter (carboxyfluorescein diacetate, CFDA) and a hapten (dinitrophenyl
A highly flexible dinuclear ruthenium(II)-platinum(II) complex: crystal structure and binding to 9-ethylguanine.
Karlijn van der Schilden et al.
Angewandte Chemie (International ed. in English), 43(42), 5668-5670 (2004-10-21)
Flavia Barragán et al.
Journal of the American Chemical Society, 133(35), 14098-14108 (2011-07-30)
A photoactivated ruthenium(II) arene complex has been conjugated to two receptor-binding peptides, a dicarba analogue of octreotide and the Arg-Gly-Asp (RGD) tripeptide. These peptides can act as "tumor-targeting devices" since their receptors are overexpressed on the membranes of tumor cells.
Sudeshna Roy et al.
Journal of inorganic biochemistry, 103(9), 1278-1287 (2009-08-07)
Two chelating ligands based on secondary amines have been selected to prepare four new Pt(II) compounds. The ligands bis(pyridine-2-yl)amine, abbreviated dpa, and bis(pyrimidine-2-yl)amine, abbreviated dipm, are chosen to design a rigid chelating motif to allow the study of subtle differences
Seiji Komeda et al.
Journal of the American Chemical Society, 124(17), 4738-4746 (2002-04-25)
The reactions of the dinuclear platinum(II) complexes, [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-pz)](NO(3))(2) (1, pz = pyrazolate), [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-1,2,3-ta-N1,N2)](NO(3))(2) (2, 1,2,3-ta = 1,2,3-triazolate), and a newly prepared [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-4-phe-1,2,3-ta-N1,N2)](NO(3))(2) (3, 4-phe-1,2,3-ta = 4-phenyl-1,2,3-triazolate), whose crystal structure was determined, with 9-ethylguanine (9EtG) have been monitored in aqueous solution

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