F0393
2′-Fucosyl-D-lactose
from human milk, ≥98% (HPAE/PAD)
别名:
α-L-Fuc-(1→2)-β-D-Gal-(1→4)-D-Glc
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关于此项目
经验公式（希尔记法）:
C18H32O15
化学文摘社编号:
分子量:
488.44
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
biological source
human milk
assay
≥98% (HPAE/PAD)
form
powder
solubility
H2O: 2 mg + 0.2 mL, clear, colorless
storage temp.
2-8°C
SMILES string
C[C@@H]1O[C@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O)C(O)O[C@@H]3CO)[C@@H](O)[C@H](O)[C@@H]1O
InChI
1S/C18H32O15/c1-4-7(21)9(23)13(27)17(29-4)33-15-10(24)8(22)5(2-19)31-18(15)32-14-6(3-20)30-16(28)12(26)11(14)25/h4-28H,2-3H2,1H3/t4-,5+,6+,7+,8-,9+,10-,11+,12+,13-,14+,15+,16?,17+,18-/m0/s1
InChI key
SNFSYLYCDAVZGP-ZTFPOLCTSA-N
Application
2′-Fucosyl-D-lactose is used as substrate to identify, differentiate and characterize fucosidases. It is also used in the development of biosensors to identify anti-infective oligosaccharides. 2′-Fucosyl-D-lactose is used to differentiate IL-8 receptor specificity and function. It may be used to study is effects on intestinal microbiota and as a reference compound in assays developed to detect and measure milk sugars.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Nikola Kostlánová et al.
The Journal of biological chemistry, 280(30), 27839-27849 (2005-06-01)
Plant pathogens, like animal ones, use protein-carbohydrate interactions in their strategy for host recognition, attachment, and invasion. The bacterium Ralstonia solanacearum, which is distributed worldwide and causes lethal wilt in many agricultural crops, was shown to produce a potent L-fucose-binding
Determination of the structures of fucosyl-lactose and difucosyl-lactose from the milk of monotremes, using 13C-n.m.r. spectroscopy.
G A Jenkins et al.
Carbohydrate research, 126(1), 157-161 (1984-03-01)
Myriam Coulet et al.
Regulatory toxicology and pharmacology : RTP, 68(1), 59-69 (2013-11-23)
In order to match the composition of human breast milk more closely, it is now possible to supplement commercial infant formula (IF) with synthesised oligosaccharides that are chemically identical to human milk oligosaccharides. The safety data generated on a new